SFB889 Cellular Mechanisms of Sensory Processing

Publications

check publications in: 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011

2017


July 26th, 2017
Inference of neuronal functional circuitry with spike-triggered non-negative matrix factorization
Liu JK, Schreyer HM, Onken A, Rozenblit F, Khani MH, Krishnamoorthy V, Panzeri S, Gollisch T

Nature Communications, 2017 Jul 26, 8, (149); doi:10.1038/s41467-017-00156-9.

July 14th, 2017
Loss of Neuroligin3 specifically downregulates retinal GABAAα2 receptors without abolishing direction selectivity
Hoon M, Krishnamoorthy V, Gollisch T, Falkenburger B, Varoqueaux F

PLoS, 2017 Jul 14; doi.org/10.1371/journal.pone.0181011.

July 11th, 2017
SIFamide Translates Hunger Signals into Appetitive and Feeding Behavior in Drosophila
Martelli C, Pech U, Kobbenbring S, Pauls D, Bahl B, Sommer MV, Pooryasin A, Barth J, Warth Perez Arias C, Vassiliou C, Farca Luna AJ, Poppinga H, Richter FG, Wegener C, Fiala A, Riemensperger T

Cell Reports. 2017 Jul 11; 20, (2): 464–478. doi.org/10.1016/j.celrep.2017.06.043.

June 6th, 2017
What makes a reach movement effortful? Physical effort discounting supports common minimization principles in decision making and motor control
Morel P, Ulbrich P, Gail A

PLoS Biol. 2017 Jun 6;15(6):e2001323. doi: 10.1371/journal.pbio.2001323. eCollection 2017 Jun.

May 22nd, 2017
Rab interacting molecules 2 and 3 directly interact with the pore-forming CaV1.3 Ca2+ channel subunit and promote its membrane expression
Picher MM, Oprişoreanu AM, Jung S, Michel K, Schoch S, Moser T

Frontiers in Cellular Neuroscience, in press.

April 19th, 2017
Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate
Release.
Sigler A, Oh WC, Imig C, Altas B, Kawabe H, Cooper BH, Kwon HB, Rhee JS, Brose N

Neuron. 2017 Apr 19;94(2):304-311.e4; doi: 10.1016/j.neuron.2017.03.029.

March 6th, 2017
Conditional deletion of pejvakin in adult outer hair cells causes progressive hearing loss
in mice.
Harris SL, Kazmierczak M, Pangršič T, Shah P, Chuchvara N, Barrantes-Freer A, Moser T,
Schwander M

Neuroscience. 2017 Mar 6;344:380-393; doi: 10.1016/j.neuroscience.2016.12.055. Epub 2017 Jan 9.

February 22nd, 2017
Sensitivity to image recurrence across eye-movement-like image transitions through local serial inhibition in the retina.
Krishnamoorthy V, Weick M, Gollisch T

Elife. 2017 Feb 23;6. pii: e22431; doi: 10.7554/eLife.22431.

February 3rd, 2017
Regulation of Dendritic Spine Morphology in Hippocampal Neurons by Copine-6.
Burk K, Ramachandran B, Ahmed S, Hurtado-Zavala JI, Awasthi A, Benito E, Faram R, Ahmad H, Swaminathan A, McIlhinney J, Fischer A, Perestenko P, Dean C

Cereb Cortex. 2017 Feb 3:1-18; doi: 10.1093/cercor/bhx009.

January 11th, 2017
Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place
preference.
Shukla A, Beroun A, Panopoulou M, Neumann PA, Grant SGN, Olive MF, Dong Y, Schlüter OM

EMBO J. 2017 Feb 15;36(4):458-474; doi: 10.15252/embj.201695465. Epub 2017 Jan 11.

January 23rd, 2017
Hearing regulates Drosophila aggression.
Versteven M, Vande Broeck L, Geurten B, Zwarts L, Decraecker L, Beelena M, Göpfert MC,
Heinrich R, Callaerts P

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1958-1963, Epub 2017 Jan 23; doi: 10.1073/pnas.1605946114.

January 18th, 2017
Adrenergic Gate Release for Spike Timing-Dependent Synaptic Potentiation.
Liu Y, Cui L, Schwarz MK, Dong Y, Schlüter OM

Neuron. 2017 Jan 18;93(2):394-408; doi: 10.1016/j.neuron.2016.12.039.

January 5th, 2017
Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells.
Picher MM, Gehrt A, Meese S, Ivanovic A, Predoehl F, Jung S, Schrauwen I, Dragonetti AG,
Colombo R, Van Camp G, Strenzke N, Moser T

Proc Natl Acad Sci USA. 2017 Feb 9. pii: 201617533; doi: 10.1073/pnas.1617533114.

January 1st, 2017
Differential Contribution of Low- and High-level Image Content to Eye Movements in Monkeys
and Humans.
Kietzmann TC, Jutras M, Xue C, Treue S, Buffalo EA, König P

Cereb Cortex. 2017 Jan 1;27(1):279-293; doi: 10.1093/cercor/bhw399.

2016


December 1st, 2016
A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and
vesicle recycling in astrocytic processes.
Wolfes AC, Ahmed S, Awasthi A, Stahlberg MA, Rajput A, Magruder DS, Bonn S, Dean C

J Gen Physiol. 2017 Jan;149(1):149-170; Epub 2016 Dec 1; doi: 10.1085/jgp.201611607.

November 30th, 2016
Joint encoding of object motion and motion direction in the salamander retina.
Kühn NK, Gollisch T

Journal of Neuroscience 30 November 2016, 36 (48) 12203-12216; doi: 10.1523/JNEUROSCI.1971-16.2016.

November 29th, 2016
Parvalbumin- and vasoactive intestinal polypeptide-expressing neocortical interneurons impose differential inhibition on Martinotti cells.
Walker F, Möck M, Feyerabend M, Guy J, Wagener RJ, Schubert D, Staiger JF, Witte M

Nature Comunications 7:13664; doi: 10.1038/ncomms13664, 2016.

November 22nd, 2016
Spatial attention reduces burstiness in Mmcaque visual cortical area MST.
Xue C, Kaping D, Baloni Ray S, Krishna BS, Treue S

Cereb Cortex 1-9. 22 November 2016; doi: 10.1093/cercor/bhw326.

November 4th, 2016
Using Matrix and Tensor Factorizations for the Single-Trial Analysis of Population Spike Trains.
Onken A, Liu JK, Karunasekara PPCR, Delis I, Gollisch T, Panzeri S

PLoS Comput Biol. 2016 Nov 4;12(11):e1005189. doi: 10.1371/journal.pcbi.1005189. eCollection 2016 Nov.

October 18th, 2016
Endophilin-A deficiency induces the Foxo3a-Fbxo32 network in the brain and causes dysregulation of autophagy and the ubiquitin-proteasome system.
Murdoch JD, Rostosky CM, Gowrisankaran S, Arora AS, Soukup SF, Vidal R, Capece V, Freytag S, Fischer A, Verstreken P, Bonn S, Raimundo N, Milosevic I

Cell Rep. 2016 Oct 5. pii: S2211-1247(16)31314-6. doi: 10.1016/j.celrep.2016.09.058.

October 11th, 2016
Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants.
Strenzke N, Chakrabarti R, Al-Moyed H, Müller A, Hoch G, Pangrsic T, Yamanbaeva G, Lenz C, Pan KT, Auge E, Geiss-Friedlander R, Urlaub H, Brose N, Wichmann C, Reisinger E

EMBO J. 2016 Dec 1;35(23):2519-2535. Epub 2016 Oct 11.

September 29th, 2016
Spermidine suppresses age-associated memory impairment by preventing adverse increase of presynaptic active zone size and release.
Gupta VK, Pech U, Bhukel A, Fulterer A, Ender A, Mauermann SF, Andlauer TF, Antwi-Adjei E, Beuschel C, Thriene K, Maglione M, Quentin C, Bushow R, Schwärzel M, Mielke T, Madeo F, Dengjel J, Fiala A, Sigrist SJ

PLoS Biol. 2016 Sep 29;14(9):e1002563. doi: 10.1371/journal.pbio.1002563. eCollection 2016.

September 21st, 2016
Physical exercise preserves adult visual plasticity in mice and restores it after a stroke in the somatosensory cortex.
Kalogeraki E, Pielecka-Fortuna J, Hüppe JM, Löwel S

Front Aging Neurosci. 2016 Sep 21;8:212. eCollection 2016.

September 1st, 2016
The antiproliferative effect of bevacizumab on human tenon fibroblasts is not mediated by vascular endothelial growth factor inhibition.
Fischer CV, Mans V, Horn M, Naxer S, Klettner A, van Oterendorp C

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4970-4977. doi: 10.1167/iovs.16-19938.

August 22nd, 2016
A reanalysis of "Two types of asynchronous activity in networks of excitatory and inhibitory spiking neurons".
Engelken R, Farkhooi F, Hansel D, van Vreeswijk C, Wolf F.

F1000Res. 2016 Aug 22;5:2043.

August 15th, 2016
Uniting functional network topology and oscillations in the fronto-parietal single unit network of behaving primates.
Dann B, Michaels JA, Schaffelhofer S, Scherberger H

Elife. 2016 Aug 15;5. pii: e15719. doi: 10.7554/eLife.15719.

August 9th, 2016
Hair cells employ active zones with different voltage-dependence of Ca2+-influx to decompose sounds into complementary neural codes.
Ohn TL, Rutherford MA, Jing Z, Jung S, Duque-Afonso CJ, Hoch G, Picher MM, Scharinger A, Strenzke N, Moser T

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4716-25. doi: 10.1073/pnas.1605737113.

August 5th, 2016
Native piezo2 interactomics identifies pericentrin as a novel regulator of piezo2 in somatosensory neurons.
Narayanan P, Sondermann J, Rouwette T, Karaca S, Urlaub H, Mitkovski M, Gomez-Varela D, Schmidt M

J Proteome Res. 2016 Aug 5;15(8):2676-87. doi: 10.1021/acs.jproteome.6b00235. Epub 2016 Jul 11.

July 25th, 2016
Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.
Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing S, Vilardi F, Indzhykulian A, Pangršič T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, Kwan KY, del Castillo I, Schwappach B, Strenzke N, Corey DP, Lin SY, Moser T

EMBO J. 2016 Dec 1;35(23):2536-2552. Epub 2016 Jul 25.

July 6th, 2016
Sensing pH with TMCs.
Spalthoff C, Göpfert M

Neuron. 2016 Jul 6;91(1):6-8. doi: 10.1016/j.neuron.2016.06.026.

June 30th, 2016
Nocistatin sensitizes TRPA1 channels in peripheral sensory neurons.
Avenali L, Abate Fulas O, Sondermann J, Narayanan P, Gomez-Varela D, Schmidt M

Channels (Austin). 2016 Jun 30:1-9.

June 7th, 2016
Complexin 3 increases the fidelity of signaling in a retinal circuit by regulating exocytosis at ribbon synapses.
Mortensen LS, Park SJ, Ke JB, Cooper BH, Zhang L, Imig C, Löwel S, Reim K, Brose N, Demb JB, Rhee JS, Singer JH

Cell Rep. 2016 Jun 7;15(10):2239-50. doi: 10.1016/j.celrep.2016.05.012

March 1st, 2016
Ocular dominance plasticity after stroke was preserved in PSD-95 knockout mice.
Greifzu F, Parthier D, Goetze B, Schlüter OM, Löwel S

PLoS One. 2016 Mar 1;11(3):e0149771. doi: 10.1371/journal.pone.0149771

February 22nd, 2016
An attention-sensitive memory trace in macaque MT following saccadic eye movements.
Yao T, Treue S, Krishna BS

PLoS Biol 14(2): e1002390. doi:10.1371/journal.pbio.1002390

February 21st, 2016
Environmental enrichment preserved lifelong ocular dominance plasticity, but did not improve visual abilities.
Greifzu, F., Kalogeraki, E.,Löwel, S

Neurobiol Aging. 2016 May; 41:130-7. doi:10.1016/j.neurobiolaging.2016.02.014.

February 19th, 2016
Auditory neuropathy - neural and synaptic mechanisms.
Moser T, Starr A

Nat Rev Neurol. 2016 Feb 19. doi: 10.1038/nrneurol.2016.10. [Epub ahead of print]

January 6th, 2016
The membrane marker mCLING reveals the molecular composition of trafficking organelles.
Revelo NH, Rizzoli SO

Curr Protoc Neurosci. 2016 Jan 4;74:2.25.1-21. doi: 10.1002/0471142301.ns0225s74.

2015


December 22nd, 2015
Attention Decreases Phase-Amplitude Coupling, Enhancing Stimulus Discriminability in Cortical Area MT.
Esghaei M, Daliri MR, Treue S

Front Neural Circuits. 2015 Dec 22;9:82. doi: 10.3389/fncir.2015.00082.

December 21st, 2015
A Class of Visual Neurons with Wide-Field Properties Is Required for Local Motion Detection.
Fisher YE , Leong JCS, Sporar K, Ketkar MD, Gohl D M, Clandinin TR, Silies M

Current Biology 2015 Dec 05. DOI: http://dx.doi.org/10.1016/j.cub.2015.11.018 [Epub ahead of print]

December 11th, 2015
Hearing in Insects.
Göpfert MC, Hennig RM.

Annu Rev Entomol. 2015 Dec 11. [Epub ahead of print]

November 26th, 2015
Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing.
Karak S, Jacobs JS, Kittelmann M, Spalthoff C, Katana R, Sivan-Loukianova E, Schon MA, Kernan MJ, Eberl DF, Göpfert MC.

Sci Rep. 2015 Nov 26;5:17085. doi: 10.1038/srep17085.

November 25th, 2015
I Plan Therefore I Choose: Free-Choice Bias Due to Prior Action-Probability but Not Action-Value.
Suriya-Arunroj L, Gail A.

Front Behav Neurosci. 2015 Nov 25;9:315. doi: 10.3389/fnbeh.2015.00315.

November 17th, 2015
Random Wiring, Ganglion Cell Mosaics, and the Functional Architecture of the Visual Cortex.
Schottdorf M, Keil W, Coppola D, White LE, Wolf F.

PLoS Comput Biol. 2015 Nov 17;11(11):e1004602. doi: 10.1371/journal.pcbi.1004602.

October 28th, 2015
Super-resolution Microscopy of Clickable Amino Acids Reveals the Effects of Fluorescent Protein Tagging on Protein Assemblies.
Vreja IC, Nikić I, Göttfert F, Bates M, Kröhnert K, Outeiro TF, Hell SW, Lemke EA, Rizzoli SO.

ACS Nano. 2015 Nov 24;9(11):11034-41. doi: 10.1021/acsnano.5b04434.

October 7th, 2015
Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.
Jung S, Maritzen T, Wichmann C, Jing Z, Neef A, Revelo NH, Al-Moyed H, Meese S, Wojcik SM, Panou I, Bulut H, Schu P, Ficner R, Reisinger E, Rizzoli SO, Neef J, Strenzke N, Haucke V, Moser T.

EMBO J. 2015 Oct 7. pii: e201591885. [Epub ahead of print]

October 7th, 2015
The Ribbon Synapse Between Type I Spiral Ganglion Neurons and Inner Hair Cells.
Rutherford MA, Moser T.

The Primary Auditory Neurons of the Mammalian Cochlea Volume 52 of the series Springer Handbook of Auditory Research pp 117-156

October 1st, 2015
Growing neuronal islands on multi-electrode arrays using an accurate positioning-μCP device.
Samhaber R, Schottdorf M, El Hady A, Bröking K, Daus A, Thielemann C, Stühmer W, Wolf F

J Neurosci Methods. 2016 Jan 15;257:194-203. doi: 10.1016/j.jneumeth.2015.09.022.

September 24th, 2015
Characterizing VIP Neurons in the Barrel Cortex of VIPcre/tdTomato Mice Reveals Layer-Specific Differences.
Prönneke A, Scheuer B, Wagener RJ, Möck M, Witte M, Staiger JF.

Cereb Cortex. 2015 Dec;25(12):4854-68. doi: 10.1093/cercor/bhv202.

September 10th, 2015
Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel.
Zhang W, Cheng LE, Kittelmann M, Li J, Petkovic M, Cheng T, Jin P, Guo Z, Göpfert MC, Jan LY, Jan YN.

Cell. 2015 Sep 10;162(6):1391-403. doi: 10.1016/j.cell.2015.08.024.

July 31st, 2015
Spike-Triggered Covariance Analysis Reveals Phenomenological Diversity of Contrast Adaptation in the Retina.
Liu KL, Gollisch T.

PLoS Comput Biol. 2015 Jul 31;11(7):e1004425. doi: 10.1371/journal.pcbi.1004425

July 23rd, 2015
Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover.
Körber C, Horstmann H, Venkataramani V, Herrmannsdörfer F, Kremer T, Kaiser M, Schwenger DB, Ahmed S, Dean C, Dresbach T, Kuner T.

Neuron. 2015 Aug 5;87(3):521-33. doi: 10.1016/j.neuron.2015.07.001.

July 8th, 2015
Gene therapy for deafness: How close are we?
Moser T.

Sci Transl Med. 2015 Jul 8;7(295):295fs28

June 26th, 2015
Synaptic encoding and processing of auditory information in physiology and disease.
Moser T & Strenzke N.

Hear Res. 2015 Dec;330(Pt B):155-6

June 16th, 2015
Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.
Jung S, Oshima-Takago T, Chakrabarti R, Wong AB, Jing Z, Yamanbaeva G, Picher MM, Wojcik SM, Göttfert F, Predoehl F, Michel K, Hell SW, Schoch S, Strenzke N, Wichmann C, Moser T.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3141-9. doi: 10.1073/pnas.1417207112.

June 3rd, 2015
Modulation of nociceptive ion channels and receptors via protein-protein interactions: implications for pain relief.
Rouwette T, Avenali L, Sondermann J, Narayanan P, Gomez-Varela D, Schmidt M.

Channels (Austin). 2015;9(4):175-85. doi: 10.1080/19336950.2015.1051270.

May 26th, 2015
Progressive maturation of silent synapses governs the duration of a critical period.
Huang X, Stodieck SK, Goetze B, Cui L, Wong MH, Wenzel C, Hosang L, Dong Y, Löwel S, Schlüter OM.

Proc Natl Acad Sci U S A. 2015 May 26; doi: 10.1073/pnas.1506488112

May 19th, 2015
What types of neocortical GABAergic neurons do really exist?
Staiger JF, Möck M, Witte M.

Neuroforum. 2015 June;6(2):49-56.

May 7th, 2015
Restoring the ON Switch in Blind Retinas: Opto-mGluR6, a Next-Generation, Cell-Tailored Optogenetic Tool.
van Wyk M, Pielecka-Fortuna J, Löwel S, Kleinlogel S.

PLoS Biol. 2015 May 7;13(5):e1002143. doi: 10.1371/journal.pbio.1002143.

May 6th, 2015
TRP Channels in Insect Stretch Receptors as Insecticide Targets.
Nesterov A, Spalthoff C, Kandasamy R, Katana R, Rankl NB, Andrés M, Jähde P, Dorsch JA, Stam LF, Braun FJ, Warren B, Salgado VL, Göpfert MC.

Neuron. 2015 May 6;86(3):665-71. doi: 10.1016/j.neuron.2015.04.001.

May 6th, 2015
Molecular Remodeling of the Presynaptic Active Zone of Drosophila Photoreceptors via Activity-Dependent Feedback.
Sugie S, Hakeda-Suzuki S, Suzuki E, Silies M, Shimozono M, Möhl C, Suzuki T, Tavosanis G.

Neuron. 2015 May 6;86(3):711-25. doi: 10.1016/j.neuron.2015.03.046.

March 31st, 2015
Optical dissection of experience-dependent pre- and postsynaptic plasticity in the Drosophila brain.
Pech U, Revelo NH, Seitz KJ, Rizzoli SO, Fiala A.

Cell Rep. 2015 Mar 31;10(12):2083-95. doi: 10.1016/j.celrep.2015.02.065. Epub 2015 Mar 26.

March 3rd, 2015
EF-hand protein Ca2+ buffers regulate Ca2+ influx and exocytosis in sensory hair cells.
Pangršič T, Gabrielaitis M, Michanski S, Schwaller B, Wolf F, Strenzke N, Moser T.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E1028-37. doi: 10.1073/pnas.1416424112. Epub 2015 Feb 17.

February 21st, 2015
Hearing in Drosophila.
Albert JT, Göpfert MC.

Curr Opin Neurobiol. 2015 Feb 21;34C:79-85. doi: 10.1016/j.conb.2015.02.001.

February 15th, 2015
Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.
Vogl C, Cooper BH, Neef J, Wojcik SM, Reim K, Reisinger E, Brose N, Rhee JS, Moser T, Wichmann C.

J Cell Sci. 2015 Feb 15;128(4):638-44. doi: 10.1242/jcs.162099. Epub 2015 Jan 20.

February 5th, 2015
Long-term depression is differentially expressed in distinct lamina of hippocampal CA1 dendrites.
Ramachandran B, Ahmed S, Dean C.

Front Cell Neurosci. 2015 Feb 5;9:23. doi: 10.3389/fncel.2015.00023.

January 28th, 2015
Optogenetic stimulation of the auditory pathway for research and future prosthetics.
Moser T.

Curr Opin Neurobiol. 2015 Jan 28;34C:29-36. doi: 10.1016/j.conb.2015.01.004. [Epub ahead of print]

January 22nd, 2015
Relating structure and function of inner hair cell ribbon synapses.
Wichmann C & Moser T.

Cell Tissue Res. 2015 Jul;361(1):95-114.

January 21st, 2015
Asymmetric generalization in adaptation to target displacement errors in humans and in a neural network model.
Westendorff S, Kuang S, Taghizadeh B, Donchin O, Gail A.

J Neurophysiol. 2015 Jan 21:jn.00483.2014. doi: 10.1152/jn.00483.2014. [Epub ahead of print]

January 16th, 2015
Considering optogenetic stimulation for cochlear implants.
Jeschke M & Moser T.

Hear Res. 2015 Apr;322:224-34. doi: 10.1016/j.heares.2015.01.005.

January 9th, 2015
Planning Movements in Visual and Physical Space in Monkey Posterior Parietal Cortex.
Kuang S, Morel P, Gail A.

Cereb Cortex. 2015 Jan 9. pii: bhu312. [Epub ahead of print]

2014


December 15th, 2014
Synchronization patterns suggest different functional organization in parietal reach region and dorsal premotor cortex.
Chakrabarti S, Martinez-Vazquez P, Gail A.

J Neurophysiol. 2014 Dec 15;112(12):3138-53. doi: 10.1152/jn.00621.2013. Epub 2014 Sep 17.

December 15th, 2014
Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools.
AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF.

Nat Commun. 2014 Dec 15;5:5810. doi: 10.1038/ncomms6810.

November 12th, 2014
Voluntary Physical Exercise Promotes Ocular Dominance Plasticity in Adult Mouse Primary Visual Cortex.
Kalogeraki E, Greifzu F, Haack F, Löwel S.

J Neurosci. 2014 Nov 12;34(46):15476-81. doi: 10.1523/JNEUROSCI.2678-14.2014.

October 30th, 2014
Application of STED Microscopy to Cell Biology Questions.
Revelo NH, Rizzoli SO.

Methods Mol Biol. 2015;1251:213-30. doi: 10.1007/978-1-4939-2080-8_12.

September 25th, 2014
Ethanol inhibits long-term potentiation in hippocampal CA1 neurons, irrespective of lamina and stimulus strength, through neurosteroidogenesis.
Ramachandran B, Ahmed S, Zafar N, Dean C.

Hippocampus. 2015 Jan;25(1):106-18. doi: 10.1002/hipo.22356.

September 23rd, 2014
Channelrhodopsin-2-XXL, a powerful optogenetic tool for low-light applications.
Dawydow A, Gueta R, Ljaschenko D, Ullrich S, Hermann M, Ehmann N, Gao S, Fiala A, Langenhan T, Nagel G, Kittel RJ.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13972-7. doi: 10.1073/pnas.1408269111. Epub 2014 Sep 8

September 16th, 2014
Brief dark exposure restored ocular dominance plasticity in aging mice and after a cortical stroke.
Stodieck SK, Greifzu F, Goetze B, Schmidt KF, Löwel S.

Exp Gerontol. 2014 Sep 16;60C:1-11. doi: 10.1016/j.exger.2014.09.007. [Epub ahead of print]

September 16th, 2014
When adaptive control fails: Slow recovery of reduced rapid online control during reaching under reversed vision
Shenbing Kuang, Alexander Gail

Vision Res. 2014 Sep 16. pii: S0042-6989(14)00208-9. doi: 10.1016/j.visres.2014.08.021.

September 3rd, 2014
Uniquantal Release through a Dynamic Fusion Pore Is a Candidate Mechanism of Hair Cell Exocytosis.
Nikolai M. Chapochnikov, Hideki Takago, Chao-Hua Huang, Tina Pangrisic, Darina Khimich, Jakob Neef, Elisabeth Auge, Fabian Göttfert, Stefan W. Hell, Carolin Wichmann, Fred Wolf and Tobias Moser

Neuron. 2014 Sep 3. pii: S0896-6273(14)00678-3. doi: 10.1016/j.neuron.2014.08.003. [Epub ahead of print]

August 31th, 2014
Photo-cross-linking and high-resolution mass spectrometry for assignment of RNRNA-binding sites in RNRNA-binding proteins
Katharina Kramer, Timo Sachsenberg, Benedikt M Beckmann, Saadia Qamar, Kum-Loong Boon, Matthias W Hentze, Oliver Kohlbacher & Henning Urlaub

Nat Methods. 2014 Aug 31. doi: 10.1038/nmeth.3092. [Epub ahead of print]

August 29th, 2014
Spatial task context makes short-latency reaches prone to induced Roelofs illusion.
Bahareh Taghizadeh, Alexander Gail

Front. Hum. Neurosci., 29 August 2014 | doi: 10.3389/fnhum.2014.00673.

August 26th, 2014
Cortico-Cortical Interactions Influence Binocularity of the Primary Visual Cortex of Adult Mice.
Dehmel S, Löwel S.

PLoS One. 2014 Aug 26;9(8):e105745. doi: 10.1371/journal.pone.0105745. eCollection 2014.

August 25th, 2014
Neuronal Osmotransduction: Push-Activating TRPV1 with Microtubules.
Andrés M, Göpfert MC.

Dev Cell. 2014 Aug 25;30(4):363-4. doi: 10.1016/j.devcel.2014.08.012.

August 15th, 2014
The disorganized visual cortex in reelin-deficient mice is functional and allows for enhanced plasticity.
Justyna Pielecka-Fortuna, Robin Jan Wagener, Ann-Kristin Martens, Bianka Goetze, Karl-Friedrich Schmidt, Jochen F. Staiger, Siegrid Löwel

Brain Struct Funct. 2014 Aug 15. [Epub ahead of print]

August 10th, 2014
Optogenetic Stimulation of the Auditory Nerve
Victor H. Hernandez, Anna Gehrt, Zhizi Jing, Gerhard Hoch, Marcus Jeschke, Nicola Strenzke, Tobias Moser

JoVE. 10/08/2014, Issue 92; doi: 10.3791/52069

July 25th, 2014
Multi-protein assemblies underlie the mesoscale organization of the plasma membrane.
Saka SK, Honigmann A, Eggeling C, Hell SW, Lang T, Rizzoli SO

Nat Commun. 2014 Jul 25;5:4509. doi: 10.1038/ncomms5509.

May 30th, 2014
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, Rizzoli SO.

Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.

May 28th, 2014
ial integration in the receptive field surround of retinal ganglion cells.
Takeshita D, Gollisch T.

J Neurosci. 2014 May 28;34(22):7548-61. doi: 10.1523/JNEUROSCI.0413-14.2014.

May 26th, 2014
A new probe for super-resolution imaging of membranes elucidates trafficking pathways.
Revelo NH, Kamin D, Truckenbrodt S, Wong AB, Reuter-Jessen K, Reisinger E, Moser T, Rizzoli SO.

J Cell Biol. 2014 May 26;205(4):591-606. doi: 10.1083/jcb.201402066.

May 15th, 2014
Induction of aversive learning through thermogenetic activation of Kenyon cell ensembles in Drosophila.
Vasmer D, Pooryasin A, Riemensperger T, Fiala A

Front. Behav. Neurosci., 15 May 2014 | doi: 10.3389/fnbeh.2014.00174.

May 14th, 2014
ATP Hydrolysis Is Critically Required for Function of CaV1.3 Channels in Cochlear Inner Hair Cells via Fueling Ca2+ Clearance.
Weiler S, Krinner S, Wong AB, Moser T, Pangršič T

J Neurosci. 2014 May 14;34(20):6843-8. doi: 10.1523/JNEUROSCI.4990-13.2014.

April 23rd, 2014
Persistence of Functional Sensory Maps in the Absence of Cortical Layers in the Somsatosensory Cortex of Reeler Mice.
Guy J, Wagener RJ, Möck M, Staiger JF

Cereb. Cortex (2014) doi: 10.1093/cercor/bhu052

April 18th, 2014
TRPs in Hearing
Zanini D, Göpfert MC.

Handb Exp Pharmacol. 2014;223:899-916. doi: 10.1007/978-3-319-05161-1_7.

April 10th, 2014
Correlated optical and isotopic nanoscopy.
Saka SK, Vogts A, Kröhnert K, Hillion F, Rizzoli SO, Wessels JT.

Nat Commun. 2014 Apr 10;5:3664. doi: 10.1038/ncomms4664.

February 26th, 2014
A gradual depth-dependent change in connectivity features of supragranular pyramidal cells in rat barrel cortex
Staiger JF, Bojak I, Miceli S, Schubert D

Brain Struct Funct. 2014 Feb 26. [Epub ahead of print]

February 19th, 2014
hemingway is required for sperm flagella assembly and ciliary motility in Drosophila.
Soulavie F, Piepenbrock D, Thomas J, Vieillard J, Duteyrat JL, Cortier E, Laurençon A, Göpfert MC, Durand B.

Mol Biol Cell. 2014 Apr;25(8):1276-86. doi: 10.1091/mbc.E13-10-0616. Epub 2014 Feb 19.

February 5th, 2014
FM dye photo-oxidation as a tool for monitoring membrane recycling in inner hair cells.
Kamin D, Revelo NH, Rizzoli SO

PLoS One. 2014 Feb 5;9(2):e88353. doi: 10.1371/journal.pone.0088353. eCollection 2014.

February 4th, 2014
The extracellular matrix protein artichoke is required for integrity of ciliated mechanosensory and chemosensory organs in Drosophila embryos.
Andrés M, Turiégano E, Göpfert MC, Canal I, Torroja L.

Genetics. 2014 Apr;196(4):1091-102. doi: 10.1534/genetics.113.156323. Epub 2014 Feb 4.

January 29th, 2014
Differential Associative Training Enhances Olfactory Acuity in Drosophila melanogaster.
Barth J, Dipt S, Pech U, Hermann M, Riemensperger T, Fiala A.

J Neurosci. 2014 Jan 29;34(5):1819-37. doi: 10.1523/JNEUROSCI.2598-13.2014.

January 17th, 2014
Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis
Wong AB, Rutherford MA, Gabrielaitis M, Pangršič T, Göttfert F, Frank T, Michanski S, Hell S, Wolf F, Wichmann C, Moser T

The EMBO Journal

January 17th, 2014
Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse
Mendoza Schulz A, Jing Z, Sánchez Caro JM, Wetzel F, Dresbach T, Strenzke N, Wichmann C, Moser T

The EMBO Journal

January 15th, 2014
Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells
Neef J, Jung S, Wong AB, Reuter K, Pangrsic T, Chakrabarti R, Kügler S, Lenz C, Nouvian R, Boumil RM, Frankel WN, Wichmann C, Moser T.

J Neurosci. 2014 Jan 15;34(3):705-16. doi: 10.1523/JNEUROSCI.3313-13.2014.

January 6th, 2014
Environmental enrichment extends ocular dominance plasticity into adulthood and protects from stroke-induced impairments of plasticity
Greifzu F, Pielecka-Fortuna J, Kalogeraki E, Krempler K, Favaro PD, Schlüter OM, Löwel S..

Proc Natl Acad Sci U S A. 2014 Jan 6. [Epub ahead of print]

2013


December 12th, 2013
A global in vivo Drosophila RNAi screen identifies a key role of ceramide phosphoethanolamine for glial ensheathment of axons
Aniket Ghosh, Tina Kling, Nicolas Snaidero, Julio L. Sampaio, Andrej Shevchenko, Heribert Gras, Bart Geurten, Martin C. Göpfert, Jörg B. Schulz, Aaron Voigt, Mikael Simons

CPLoS Genet. 2013;9(12):e1003980. doi: 10.1371/journal.pgen.1003980. Epub 2013 Dec 12.

November 14th, 2013
A single dopamine pathway underlies progressive locomotor deficits in a Drosophila model of Parkinson disease
Riemensperger T, Issa AR, Pech U, Coulom H, Nguyễn MV, Cassar M, Jacquet M, Fiala A, Birman S.

Cell Rep. 2013 Nov 27;5(4):952-60. doi: 10.1016/j.celrep.2013.10.032. Epub 2013 Nov 14.

September 25th, 2013
Opposite adaptive processing of stimulus intensity in two major nuclei of the somatosensory brainstem.
Mohar B, Katz Y, Lampl I.

J Neurosci. 2013 Sep 25;33(39):15394-400. doi: 10.1523/JNEUROSCI.1886-13.2013.

September 25th, 2013
Differential Roles of Postsynaptic Density-93 Isoforms in Regulating Synaptic Transmission
Krüger JM, Favaro PD, Liu M, Kitlinska A, Huang X, Raabe M, Akad DS, Liu Y, Urlaub H, Dong Y, Xu W, Schlüter OM

J Neurosci. 2013 Sep 25;33(39):15504-15517

September 23rd, 2013
Mushroom body miscellanea: transgenic Drosophila strains expressing anatomical and physiological sensor proteins in Kenyon cells
Pech U, Dipt S, Barth J, Singh P, Jauch M, Thum AS, Fiala A, Riemensperger T.

Front Neural Circuits. 2013 Sep 23;7:147. doi: 10.3389/fncir.2013.00147

September 4th, 2013
Cortical balance of excitation and inhibition is regulated by the rate of synaptic activity.
Taub AH, Katz Y, Lampl I.

J Neurosci. 2013 Sep 4;33(36):14359-68. doi: 10.1523/JNEUROSCI.1748-13.2013.

August 19th, 2013
The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles
Matkovic T, Siebert M, Knoche E, Depner H, Mertel S, Owald D, Schmidt M, Thomas U, Sickmann A, Kamin D, Hell SW, Bürger J, Hollmann C, Mielke T, Wichmann C, Sigrist SJ

J Cell Biol. 2013 Aug 19;202(4):667-83. doi: 10.1083/jcb.201301072

August 14th, 2013
Synaptic State-Dependent Functional Interplay between Postsynaptic Density-95 and Synapse-Associated Protein 102
Bonnet SA, Akad DS, Samaddar T, Liu Y, Huang X, Dong Y, Schlüter OM.

J Neurosci. 2013 Aug 14;33(33):13398-409. doi: 10.1523/JNEUROSCI.6255-11.2013

July 10th, 2013
Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.
Lipstein N, Sakaba T, Cooper BH, Lin KH, Strenzke N, Ashery U, Rhee JS, Taschenberger H, Neher E, Brose N.

Neuron. 2013 Jul 10;79(1):82-96. doi: 10.1016/j.neuron.2013.05.011. Epub 2013 Jun 13.

June 26th, 2013
Concurrent maturation of inner hair cell synaptic Ca2+influx and auditory nerve spontaneous activity around hearing onset in mice
Aaron B Wong, Zhizi Jing, Mark A Rutherford, Thomas Frank, Nicola Strenzke and Tobias Moser

J Neurosci. 2013 Jun 26;33(26):10661-6. doi: 10.1523/JNEUROSCI.1215-13.2013.

June 20th, 2013
Localization of the contacts between Kenyon cells and aminergic neurons in the Drosophila melanogaster brain using splitGFP reconstitution
Pech U, Pooryasin A, Birman S, Fiala A.

J Comp Neurol. 2013 Jun 20. doi: 10.1002/cne.23388. [Epub ahead of print].

May 28th, 2013
Mover is a homomeric phospho-protein present on synaptic vesicles
Ahmed S, Wittenmayer N, Kremer T, Hoeber J, Kiran Akula A, Urlaub H, Islinger M, Kirsch J, Dean C, Dresbach T.

PLoS One. 2013 May 28;8(5):e63474. doi: 10.1371/journal.pone.0063474. Print 2013.

May 8th, 2013
Imbalance between Excitation and Inhibition in the Somatosensory Cortex Produces Postadaptation Facilitation
Katayun Cohen-Kashi Malina, Muna Jubran, Yonatan Katz and Ilan Lampl

J Neurosci. 2013 May 8;33(19):8463-71. doi: 10.1523/JNEUROSCI.4845-12.2013.

May 6th, 2013
Mechanosensation: tethered ion channels.
Zanini D, Göpfert MC.

Curr Biol. 2013 May 6;23(9):R349-51. doi: 10.1016/j.cub.2013.03.045.

April 29th, 2013
"Self" versus "non-self" connectivity dictates properties of synaptic transmission and plasticity.
Liu H, Chapman ER, Dean C.

PLoS One. 2013 Apr 29;8(4):e62414. doi: 10.1371/journal.pone.0062414.

April 24th, 2013
Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses
Boyken J, Grønborg M, Riedel D, Urlaub H, Jahn R, Chua JJ.

Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027

April 22nd, 2013
Harmonin enhances voltage-dependent facilitation of Cav1.3 channels and synchronous exocytosis in mouse inner hair cells
Gregory FD, Pangrsic T, Calin-Jageman IE, Moser T, Lee A.

J Physiol. 2013 Apr 22. [Epub ahead of print]

April 17th, 2013
Controlling the oscillation phase through precisely timed closed-loop optogenetic stimulation: a computational study
Witt A, Palmigiano A, Neef A, El Hady A, Wolf F, Battaglia D.

Front Neural Circuits. 2013 Apr 17;7:49. doi: 10.3389/fncir.2013.00049. eCollection 2013.

March 30th, 2013
Optopatcher-An electrode holder for simultaneous intracellular patch-clamp recording and optical manipulation
Katz Y, Yizhar O, Staiger J, Lampl I.

Neurosci Methods. 2013 Mar 30;214(1):113-7. doi: 10.1016/j.jneumeth.2013.01.017. Epub 2013 Jan 28.

March 6th, 2013
Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multi-quantal release, and sound encoding at the hair cell afferent synaps.
Zhizi Jing, Mark A. Rutherford, Hideki Takago, Thomas Frank, Anna Fejtova, Darina Khimich, Tobias Moser, Nicola Strenzke

The Journal of Neuroscience, 6 March 2013, 33(10): 4456-4467; doi: 10.1523/JNEUROSCI.3491-12.2013

March 6th, 2013
Local and Global Contrast Adaptation in Retinal Ganglion Cells
Garvert MM, Gollisch T

Neuron. 2013 Mar 6;77(5):915-28. doi: 10.1016/j.neuron.2012.12.030.

February 5th, 2013
Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells
Defourny J, Poirrier AL, Lallemend F, Mateo Sánchez S, Neef J, Vanderhaeghen P, Soriano E, Peuckert C, Kullander K, Fritzsch B, Nguyen L, Moonen G, Moser T, Malgrange B.

Nat Commun. 2013;4:1438. doi: 10.1038/ncomms2445.

January 2nd, 2013
Computing Complex Visual Features with Retinal Spike Times
Gütig R*, Gollisch T*, Sompolinsky H, Meister M

PLoS One 2013, 8(1):e53063 (*=equal contribution)

2012


Dec 20th, 2012
Dynamic Flux Tubes Form Reservoirs of Stability in Neuronal Circuits
Michael Monteforte and Fred Wolf

Phys. Rev. X 2, 041007 (2012) [12 pages]

Dec 20th, 2012
Features and Functions of ial Integration by Retinal Ganglion Cells
Gollisch T

Journal of Physiology Paris 2012, Epub ahead of print, doi: 10.1016/j.jphysparis.2012.12.001

Dec 19th, 2012
The Iso-Response Method: Measuring Neuronal Stimulus Integration with Closed-Loop Experiments.
Gollisch T, Herz AVM

Front Neural Circuits. 2012;6:104. doi: 10.3389/fncir.2012.00104. Epub 2012 Dec 19.

Nov 8th, 2012
Coordinated optimization of visual cortical maps (II) numerical studies
Reichl L, Heide D, Löwel S, Crowley JC, Kaschube M, Wolf F.

PLoS Comput Biol. 2012;8(11):e1002756. doi: 10.1371/journal.pcbi.1002756. Epub 2012 Nov 8.

Nov 8th, 2012
Coordinated optimization of visual cortical maps (I) symmetry-based analysis
Reichl L, Heide D, Löwel S, Crowley JC, Kaschube M, Wolf F.

PLoS Comput Biol. 2012;8(11):e1002466. doi: 10.1371/journal.pcbi.1002466. Epub 2012 Nov 8.

Nov 8th, 2012
Sensorimotor learning biases choice behavior: a learning neural field model for decision making
Klaes C, Schneegans S, Schöner G, Gail A.

PLoS Comput Biol. 2012 Nov;8(11):e1002774. doi: 10.1371/journal.pcbi.1002774

Oct, 2012
Transcranial alternating stimulation in a high gamma frequency range applied over V1 improves contrast perception but does not modulate spatial attention
Laczó B, Antal A, Niebergall R, Treue S, Paulus W.

Brain Stimul. 2012 Oct;5(4):484-91. doi: 10.1016/j.brs.2011.08.008. Epub 2011 Sep 15.

Sep 9th, 2012
Improving behavioral performance under full attention by adjusting response criteria to changes in stimulus predictability
Katzner S, Treue S, Busse L.

Journal of Vision 2012 Sep 4;12(10). pii: 1. doi: 10.1167/12.10.1. Print 2012.

Sep 6th, 2012
Otoferlin: a multi-C2 domain protein essential for hearing
Tina Pangršič, Ellen Reisinger, Tobias Moser

Sound is encoded at synapses between cochlear inner hair cells and the auditory nerve. These synapses are anatomically and functionally specialized to transmit acoustic information with high fidelity over a lifetime. The molecular mechanisms of hair-cell transmitter release have recently attracted substantial interest. Here we review progress toward understanding otoferlin, a multi-C2 domain protein identified a decade ago by genetic analysis of human deafness. Otoferlin functions in hair-cell exocytosis. Several otoferlin C2 domains bind to Ca2+, phospholipids, and proteins. Current research reveals requirements for otoferlin in priming and fusion of synaptic vesicles during sound encoding. Understanding the molecular mechanisms through which otoferlin functions also has important implications for understanding the disease mechanisms that lead to deafness.
Trends Neurosci. 2012 Nov;35(11):671-80. doi: 10.1016/j.tins.2012.08.002. Epub 2012 Sep 7.

Aug 31st, 2012
Drosophila Auditory Organ Genes and Genetic Hearing Defects
Pingkalai R. Senthilan, David Piepenbrock, Guvanch Ovezmyradov, Björn Nadrowski, Susanne Bechstedt, Stephanie Pauls, Margret Winkler, Wiebke Möbius, Jonathon Howard, Martin C. Göpfert

The Drosophila auditory organ shares equivalent transduction mechanisms with vertebrate hair cells, and both are specified by atonal family genes. Using a whole-organ knockout strategy based on atonal, we have identified 274 Drosophila auditory organ genes. Only four of these genes had previously been associated with fly hearing, yet one in five of the genes that we identified has a human cognate that is implicated in hearing disorders. Mutant analysis of 42 genes shows that more than half of them contribute to auditory organ function, with phenotypes including hearing loss, auditory hypersusceptibility, and ringing ears. We not only discover ion channels and motors important for hearing, but also show that auditory stimulus processing involves chemoreceptor proteins as well as phototransducer components. Our findings demonstrate mechanosensory roles for ionotropic receptors and visual rhodopsins and indicate that different sensory modalities utilize common signaling cascades.
Cell. 2012 Aug 31;150(5):1042-54.

Aug 29th, 2012
Deletion of the presynaptic scaffold CAST reduces active zone size in rod photoreceptors and impairs visually evoked potentials
tom Dieck S, Specht D, Strenzke N, Hida Y, Krishnamoorthy V, Schmidt KF, Inoue E, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Hagiwara A, Brandstätter JH, Löwel S, Gollisch T, Ohtsuka T, Moser T.

J Neurosci. 2012 Aug 29;32(35):12192-12203.

Aug, 2012
Optical calcium imaging in the nervous system of Drosophila melanogaster
Riemensperger T, Pech U, Dipt S, Fiala A.

Drosophila melanogaster is one of the best-studied model organisms in biology, mainly because of the versatility of methods by which heredity and specific expression of genes can be traced and manipulated. Sophisticated genetic tools have been developed to express transgenes in selected cell types, and these techniques can be utilized to target DNA-encoded fluorescence probes to genetically defined subsets of neurons. Neuroscientists make use of this approach to monitor the activity of restricted types or subsets of neurons in the brain and the peripheral nervous system. Since membrane depolarization is typically accompanied by an increase in intracellular calcium ions, calcium-sensitive fluorescence proteins provide favorable tools to monitor the spatio-temporal activity across groups of neurons.
Biochim Biophys Acta. 2012 Aug;1820(8):1169-78. Epub 2012 Feb 28.

July 29th, 2012
Direct gating and mechanical integrity of Drosophila auditory transducers require TRPN1.
Thomas Effertz, Björn Nadrowski, David Piepenbrock, Jörg T. Albert & Martin C. Göpfert

The elusive transduction channels for hearing are directly gated mechanically by the pull of gating springs. We found that the transient receptor potential (TRP) channel TRPN1 (NOMPC) is essential for this direct gating of Drosophila auditory transduction channels and that the channel-spring complex was disrupted if TRPN1 was lost. Our results identify TRPN1 as a mechanical constituent of the fly's auditory transduction complex that may act as the channel and/or gating spring. [more]
Nature Neuroscience 2012, doi:10.1038/nn.3175

July 15th, 2012
Spike-triggered covariance: geometric proof, symmetry properties, and extension beyond Gaussian stimuli.
Samengo I, Gollisch T.

J Comput Neurosci. 2012 Jul 15. [Epub ahead of print]

June 21st, 2012
Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system
Burgalossi A, Jung S, Man KN, Nair R, Jockusch WJ, Wojcik SM, Brose N, Rhee JS

Nat Protoc. 2012 Jun 21;7(7):1351-65. doi: 10.1038/nprot.2012.074

July 11th, 2012
The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene
Geng R, Melki S, Chen DH, Tian G, Furness DN, Oshima-Takago T, Neef J, Moser T, Askew C, Horwitz G, Holt JR, Imanishi Y, Alagramam KN.

J Neurosci. 2012 Jul 11;32(28):9485-9498.

June 6th, 2012
Molecular anatomy and physiology of exocytosis in sensory hair cells
Mark A. Rutherford, Tina Pangrsic

Cell Calcium., Jun 6, 2012, DOI:10.1016/j.ceca.2012.05.008

Apr 4th, 2012
Spike Encoding of Neurotransmitter Release Timing by Spiral Ganglion Neurons of the Cochlea
Rutherford M.A., Chapochnikov N.M. and Moser T

The Journal of Neuroscience, 2012 April 4, 32(14):4773-4789, DOI:10.1523/JNEUROSCI.4511-11.2012

April 1st, 2012
Neural Circuit Development in the Mammalian Cochlea
Bulankina A. V. and Moser T

The organ of Corti, the sensory epithelium of the mammalian auditory system, uses afferent and efferent synapses for encoding auditory signals and top-down modulation of cochlear function. During development, the final precisely ordered sensorineural circuit is established following excessive formation of afferent and efferent synapses and subsequent refinement. Here, we review the development of innervation of the mouse organ of Corti and its regulation . [more]
Physiology. 2012 Apr;27(2):100-12.

March 30th, 2012
Expert-like performance of an autonomous spike tracking algorithm in isolating and maintaining single units in the macaque cortex.
Chakrabarti S, Hebert P, Wolf MT, Campos M, Burdick JW, Gail A.

J Neurosci Methods. 2012 Mar 30;205(1):72-85. doi: 10.1016/j.jneumeth.2011.12.018. Epub 2011 Dec 29.

Jan. 26th, 2012
Closed-Loop Measurements of Iso-Response Stimuli Reveal Dynamic Nonlinear Stimulus Integration in the Retina.
Daniel Bölinger, Tim Gollisch

Neurons often integrate information from multiple parallel signaling streams. How a neuron combines these inputs largely determines its computational role in signal processing. Experimental assessment of neuronal signal integration, however, is often confounded by cell-intrinsic nonlinear processes that arise after signal integration has taken place. To overcome this problem and determine how ganglion cells in the salamander retina integrate visual contrast over space, we used automated online analysis of recorded spike trains and closed-loop control of the visual stimuli to identify different stimulus patterns that give the same neuronal response. These iso-response stimuli revealed a threshold-quadratic transformation as a fundamental nonlinearity within the receptive field center. Moreover, for a subset of ganglion cells, the method revealed an additional dynamic nonlinearity that renders these cells particularly sensitive to spatially homogeneous stimuli. This function is shown to arise from a local inhibition-mediated dynamic gain control mechanism. [more]
Neuron. 2012 Jan 26;73(2):333-46.

2011


Dec 22th, 2011
Multifocal attention filters out distracter stimuli within and beyond receptive field boundaries of primate MT neurons.
Niebergall R, Khayat PS, Treue S, Martinez-Trujillo JC.

Neuron. 2011 Dec 22;72(6):1067-79.

Oct 26th, 2011
Expansion of MT neurons excitatory receptive fields during covert attentive tracking.
Niebergall R, Khayat PS, Treue S, Martinez-Trujillo JC.

J Neurosci. 2011 Oct 26;31(43):15499-510.

Oct. 20th, 2011
Representation of Dynamical Stimuli in Populations of Threshold Neurons.
Tatjana Tchumatchenko, Fred Wolf

PLoS Comput Biol. 2011 Oct;7(10):e1002239. Epub 2011 Oct 20.

Aug. 7th, 2011
Harmonin inhibits presynaptic Cav1.3 Ca2+ channels in mouse inner hair cells.
Gregory FD, Bryan KE, Pangršič T, Calin-Jageman IE, Moser T, Lee A.

Harmonin is a scaffolding protein that is required for normal mechanosensory function in hair cells. We found a presynaptic association of harmonin and Cav1.3 Ca2+ channels at the mouse inner hair cell synapse, which limits channel availability through a ubiquitin-dependent pathway. [more]
Nat Neurosci. 2011 Aug 7;14(9):1109-11. doi: 10.1038/nn.2895.

May 12th, 2011
Choosing Goals, Not Rules: Deciding among Rule-Based Action Plans.
Klaes C, Westendorff S, Chakrabarti S, Gail A.

In natural situations, movements are often directed toward locations different from that of the evoking sensory stimulus. Movement goals must then be inferred from the sensory cue based on rules. When there is uncertainty about the rule that applies for a given cue, planning a movement involves both choosing the relevant rule and computing the movement goal based on that rule. Under these conditions, it is not clear whether primates compute multiple movement goals based on all possible rules before choosing an action, or whether they first choose a rule and then only represent the movement goal associated with that rule. Supporting the former hypothesis, we show that neurons in the frontoparietal reach areas of monkeys simultaneously represent two different rule-based movement goals, which are biased by the monkeys' choice preferences. Apparently, primates choose between multiple behavioral options by weighing against each other the movement goals associated with each option. [more]
Neuron. 2011 May 12;70(3):536-48.

May 11th, 2011
Spike correlations - what can they tell about synchrony?
Tchumatchenko T, Geisel T, Volgushev M, Wolf F

Front Neurosci. 2011 May 11;5:68. doi: 10.3389/fnins.2011.00068. eCollection 2011

Apr. 12th, 2011
NompC TRP channel is essential for Drosophila sound receptor function.
Effertz T, Wiek R, Göpfert MC.

The idea that the NompC TRPN1 channel is the Drosophila transducer for hearing has been challenged by remnant sound-evoked nerve potentials in nompC nulls. We now report that NompC is essential for the function of Drosophila sound receptors and that the remnant nerve potentials of nompC mutants are contributed by gravity/wind receptor cells. Ablating the sound receptors reduces the amplitude and sensitivity of sound-evoked nerve responses, and the same effects ensued from mutations in nompC. Ablating the sound receptors also suffices to abolish mechanical amplification, which arises from active receptor motility, is linked to transduction, and also requires NompC. Calcium imaging shows that the remnant nerve potentials in nompC mutants are associated with the activity of gravity/wind receptors and that the sound receptors of the mutants fail to respond to sound. Hence, Drosophila sound receptors require NompC for mechanical signal detection and amplification, demonstrating the importance of this transient receptor potential channel for hearing and reviving the idea that the fly's auditory transducer might be NompC. [more]
Curr Biol. 2011 Apr 12;21(7):592-7. Epub 2011 Mar 31. doi:10.1016/j.cub.2011.02.048

Feb. 24th, 2011
Spike Onset Dynamics and Response Speed in Neuronal Populations
Wei W, Wolf F.

Phys Rev Lett. 2011 Feb 25;106(8):088102. Epub 2011 Feb 24.









DFG - Deutsche ForschungsgemeinschaftGeorg-August-Universität Göttingen