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Neurotalks: the upcoming neuroscience talks in Göttingen [more]- Currently we do not have open positions [more]
- Volles Haus zum „Tag der Sinne“ [more]
- Tobias Moser ist Falling Walls Life Sciences Gewinner 2022 [more]
- Land Niedersachsen fördert die vorklinische Entwicklung des optischen Cochlea Implantats [more]
- Restoring Hearing With Beams Of Light [more]
- Wissen erkennt – Nacht des Wissens an der UMG [more]
- Europäische Spitzenförderung zur Erforschung des Hörens [more]
- Tierversuche an Affen: Diskussion zum Tag des Versuchstiers [more]
- Gutes Hören ist wichtig für die Lebensqualität [more]
- It´s the rhythm that counts [more]
- Mit zunehmendem Alter wird oft das Gehör schlechter [more]
- Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse. [more]
- A mutation in ATP11A causes autosomal-dominant auditory neuropathy type 2. [more]
- Bridging the gap between presynaptic hair cell function and neural sound encoding. [more]
- Attention to visual motion suppresses neuronal and behavioral sensitivity in nearby feature space. [more]
- Pruning deficits of the developing Drosophila mushroom body result in mild impairment in associative odour learning and cause hyperactivity. [more]
- Diversity of ganglion cell responses to saccade-like image shifts in the primate retina. [more]
- GGPS1-associated muscular dystrophy with and without hearing loss. [more]
- Is there an unmet medical need for improved hearing restoration? [more]
- Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function. [more]
- WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly. [more]
- BCImat: a Matlab-based framework for Intracortical Brain-Computer Interfaces and their simulation with an artificial spiking neural network. [more]
- Visualization of learning-induced synaptic plasticity in output neurons of the Drosophila mushroom body γ-lobe. [more]
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The interdisciplinary Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing” was established by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG), took effect beginning January 1st, 2011, and was prolonged for another four years beginning January 1st, 2019.
Summary of SFB 889:
Processing of sensory information is the basis of our interaction with the outside world and sensory deficits remain a major concern and serious burden for public health. This CRC will take a multidisciplinary and integrative approach to elucidate cellular mechanisms of processing sensory information. Sensory cells and neurons feature specialized signaling machinery achieving remarkable performance, which when disturbed result in sensory dysfunction. We will study sensory transduction, synaptic transmission, neuronal plasticity and the function of neuronal networks from the level of protein complexes to behavior. Combining molecular perturbations with analysis of morphology and function of sensory systems and mathematical modeling, we will contribute to a comprehensive understanding of sensory processing and its disorders. Working on flies, rodents and primates and comparing audition, vision, olfaction and somatosensation we will explore common principles and decipher specialized mechanisms of sensory processing. Intensifying pre-existing and initiating collaborations among scientists from various university and non-university institutions is key to accomplishing our ambitious research plan.
Goals of the SFB 889 are:
- Characterization of the specialized supramolecular machinery of sensory transduction and synaptic transmission
- Unravelling of mechanisms of neuronal plasticity in sensory systems
- An improved understanding of integration and representation of sensory information in the CNS
- To contribute to an improved understanding of sensory deficits and the development of therapeutic approaches
