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Membrane Biophysics Symposium

Symposium Program

pdf Program (updated 03.12.2014)

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Day 1, Monday, 30th Sept, 2013

latest update: 25th September, 2013

08:30 – 09:00 Registration
09:00 – Welcome to Göttingen Research Campus: Heyo Kroemer, Dean of School of Medicine
Opening remarks: Tobias Moser
09:10 – 10:40 Opening lectures:
Joshua Singer
"Synaptic transmission at retinal ribbon synapses"
Henrique von Gersdorff
"Synaptic transmission at hair cell synapses"
10:40 – 11:10 Poster and Coffee pdf
11:10 – 12:40 Session 1: Molecular anatomy (Chair: Carolin Wichmann)
11:10 – 11:45 Saaid Safieddine
“Molecular physiology of the inner hair cell synapse: clues from hereditary deafness”
11:45 – 12:05 Hernan Lopez-Schier
“The centrioles govern synaptic ribbon biogenesis in hair cells”
12:05 – 12:40 Toshisa Ohtsuka
“CAST and vesicle cycling at the ribbon synapses”
12:40 – 13:40 Lunch break
13:40 – 14:30 Poster and Coffee pdf
14:30 – 16:20 Session 2: Transmission at retinal ribbon synapses I (Chair: Henrique von Gersdorff)
14:30 – 15:05 Frank Schmitz
“Membrane trafficking proteins at the photoreceptor ribbon synapse”
15:05 – 15:40 Amy Lee
“Voltage-gated Ca2+ channels at ribbon synapses”
15:40 – 16:15 Leon Lagnado
“Gain control at the ribbon synapse of retinal bipolar cells”
16:15 – 17:00 Poster and Coffee pdf
17:00 – 19:05 Session 3: Transmission at ribbon synapse of inner ear and retina(Chair: Ian Russell)
17:00 – 17:35 Felix E. Schweizer
“Diversity of Hair Cells”
17:35 – 17:55 Lena Sünke Mortensen
“A ribbon synapse specific complexin regulates specifically synchronous transmitter release in retinal bipolar cells”
17:55 – 18:15 Jakob Neef
“Quantitative nanophysiology of presynaptic Ca2+ signaling”
18:15 – 18:50 Paul A. Fuchs
“Excitation of type II cochlear afferents”
19:00 – BBQ at MPIem Cafeteria


Day 2, Tuesday, 1st Oct, 2013

08:30 – 10:20 Session 4: Transmission at inner ear ribbon synapses I (Chair: Anna Lysakowski)
08:30 – 09:05 Ellen Reisinger
“A mouse model for temperature sensitive hearing loss and auditory fatigue”
09:05 – 9:25 Albena Kantardzhieva
“Quantitative analysis of ribbons, vesicles, and cisterns at the cat inner hair cell synapse: correlations with spontaneous rate”
09:25 – 9:45 Tanvi Butola
“Role of Piccolo in high frequency transmission at the central auditory synapses”
09:45 – 10:20 Ruth Anne Eatock
“Transmitting signals and making spikes in rodent otolith organs”
10:20 – 10:50 Poster and Coffee pdf
10:50 – 12:20

Session 5: Ribbon Synapse development, structure and function(Chair: Helmut Brandstätter )

10:50 – 11:25 Petri Ala-Laurila
“Vision at its ultimate limits: Does synaptic noise matter?”
11:25 – 11:45 Aaron Wong
“Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis”
11:45 – 12:20 Haruhisa Okawa
 “Developmental mechanisms regulating axonal connections of retinal bipolar cells”
12:20 – 13:20 Lunch break
13:20 – 14:20 Poster and Coffee pdf
14:20 – 15:35 Session 6: Transmission at retinal ribbon synapses II (Chair: Chair: Jeong Seop Rhee)
14:20 – 14:55 David Zenisek
 “Ribbon and extraribbon communication between rod-bipolar cells and AII Amacrine cells”
14:55 – 15:15 Matthew Van Hook
 “Fast replenishment of the cone photoreceptor ribbon is mediated by Ca2+/Calmodulin and sets the filtering properties of synaptic transmission”
15:15 – 15:35

Christina Joselevitch
“Direct observation of vesicle transport on the synaptic ribbon”

15:35 – 16:15 Poster and Coffee pdf
16:15 – 18:20

Session 7: Transmission at inner ear ribbon synapses II (Chair: Christian Vogl)

16:15 – 16:50 Regis Nouvian
 “Spatio-temporal pattern of action potential firing in developing inner hair cells”
16:50 – 17:10

Natalia Revelo Nuncira
“Synaptic vesicle recycling is functionally segregated from constitutive membrane trafficking in presynaptic cells that lack synaptic boutons”

17:10 – 17:45

Jutta Engel
“Splice variants of Cav1.3 Ca2+ channels and auxiliary alpha2delta subunits in mature mouse inner hair cells”

17:45 – 18:20

Geng-Lin Li
“Cooperative synaptic vesicle release at a hair cell ribbon synapse”

18:20 – 18:30

Best Poster Award Ceremony


Day 3, Wednesday, 2nd Oct, 2013

08:30 – 10:30 Session 8: Transmission at inner ear ribbon synapses III (Chair: Mark A. Rutherford)
08:30 – 09:05 Rebecca Seal
“Restoration of Hearing by Viral Gene Transfer”
09:05 – 09:25 Jianxin Bao
“Calcium signaling important for noise-induced loss of ribbon synapse in the cochlea”
09:25 – 09:45 Lavinia Sheets
“Synaptic-ribbon size in zebrafish lateral-line hair cells influences the latency of afferent responses to stimuli”
09:45 – 10:20 Jean-Luc Puel
“Low spontaneous rate auditory nerve fibers: the hidden component”
10:20 – 10:30 Farewells: Helmut Brandstätter
10:30 – 10:45 Coffee break

Posters pdf

Bourien Jérôme
“A multiscale computational model of guinea pig cochlea to probe neuropathy mechanisms”
Buniello Annalisa
“WBP2-Deficient mice show progressive high-frequency hearing loss and abnormal cochlear innervation”
Chakrabarti Rituparna
“Role of Otoferlin in vesicle dynamics at the inner hair cell ribbon synapses”
Gabrielaitis Mantas
“Response heterogeneity and efficiency of sound level encoding at inner hair cell ribbon synapses in an idealized biophysical model”
Jacobo Adrian
“tba”
Jung Sangyong
“The active zone protein Rim2α is required for normal synaptic sound encoding via promoting a large number of Ca2+ channels and readily releasable vesicles”
Katiyar Rashmi
“Isolation of mouse photoreceptor to study trafficing at riboon synapses”
Löhner Martina
“tba”
Mandad Sunit
“Understanding the molecular mechanism of synaptic vesicle docking in ribbon synapses”
Meanhwan Kim
“Synaptic gain changes in the inner retina via postsynaptic plasticity”
Mehta Bhupesh
“Role of SynCAM 1 in rod bipolar cells ribbon function”
Neef Jakob
“Quantitative nanophysiology of presynaptic Ca2+ signaling”
Panou Iliana
“The tryptophan-rich basic protein (WRB) is required for hair cell exocytosis and hearing”
Picher Maria Magdalena
“The impact of Ca2+ binding protein 2 on Inner Hair Cell Cav1.3 Ca2+ channel gating”
Regus-Leidig Hanna
“Loss- and gain-of-function mutations in the Cacna1f gene differentially impact photoreceptor survival and ribbon synaptic function in the mouse retina”
Natalia Revelo Nuncira
“Inner hair cells functionally separate synaptic vesicle recycling from constitutive membrane trafficking”
Rutherford Mark
“Action Potential Generation in Spiral Ganglion Neurons”
Sendelbeck Anna
“Complexins are involved in vesicle availability at the mouse photoreceptor synaptic ribbon”
Vogl Christian
“Unconventional synaptic vesicle priming at inner hair cell ribbon synapses”
Nayak Subhashree
“Morphological analysis of ribbon synapse function”
Van Hook Matthew
“Fast replenishment of the cone photoreceptor ribbon is mediated by Ca2+/Calmodulin and sets the filtering properties of synaptic transmission”
Vincent Philippe
“Probing the Ca2+sensitivity of otoferlin-dependent exocytosis in inner ear hair cells”

(pdfFull program, latest update: 25th Sptember, 2013)